What is Centrifugation?

What is Centrifugation?

Centrifugation may be a method of separating molecules having different densities by spinning them in solution around an axis (in a centrifuge rotor) at high speed. it's one of the foremost useful and regularly employed techniques within the biology laboratory. Centrifugation is employed to gather cells, precipitate DNA, purify virus particles, and differentiate subtle differences within the conformation of molecules.

It is commonly utilized in blood laboratories for separating the components of blood. After centrifugation, the component of blood separates into three distinct parts. From below upwards, the layers are - a layer of red blood cells (RBC), a layer of white blood cells(WBC) and platelets, and a layer of plasma at the highest.

What is the Necessity for Centrifugation of Blood?

It is important to separate the cellular and liquid portions of a blood specimen as soon as possible when the test requires a sample of serum or plasma. this is often because the cells interact with the serum/plasma, altering its chemical composition and affecting test results. Each part of the blood features a different function. Separating the blood into parts lets patients get only the precise part or parts of the blood that they have. So an entire blood donation is often used for several patients.